4D ultrasound as a method to assess uterine peristalsis

ObjectiveTo study uterine peristalsis using step-by-step 4-dimensional (4D) ultrasound assessment video, explore its relationship with progesterone levels in a select vitro fertilization population, and assess the reproducibility of technique.DesignFour-dimensional retrospective analysis outcomes relation levels. The videos were also analyzed by senior doctor, junior nurse for their reproducibility.SettingInstituto Bernabeu Alicante is private clinic.Patient(s)The included 197 consecutive patients undergoing (from 2018 to 2019) history recurrent implantation failure (defined as unsuccessful total number ?3 blastocysts originated from oocyte donation cycles). Because it known that most failures are attributed quality embryo, we deemed important potential factors explaining cycles, use which decreases probability embryo-related influencing it.Intervention(s)The participants evaluated contractions serum (10–30 minutes before embryo transfer procedure). Uterine contractility (UC) was assessed recording 6-minute-long video 4D mode (Voluson E10; General Electric, Boston, MA), performed single operator (B.M.).Main Outcomes Measure(s)The seen like waves going through endometrial cavity. They counted on ×15 accelerated video. To define high-frequency UC, separated (contractions per minute [cpm]) into quartiles. highest quartile defined hypercontractility group (>1.51 cpm; n = 41), considering remaining quartiles normal (?1.51 156). Mann-Whitney U test performed. intraclass correlation coefficient used validate variability. P <.05 considered significant. SPSS version 21.0 statistical analysis. institutional review board’s approval obtained.Result(s)Overall, an average 1.1 cpm found population. There no differences between groups (hypercontractility vs. contractility) terms patient age presence any factor (adenomyosis, myomas, adhesions, or polyps). An inverse association observed UC Low (15.9 19.5 ng/mL; .027) HUP NUP group, respectively. evaluate interobserver variability 0.75 (0.63–0.85; .000).Conclusion(s)Four-dimensional provides dynamic view contractions, including directionality frequency. Even though yet title obscure definition probably associated multiple factors, subgroup elevated “low” may have effect outcomes. Four-dimensional scan evaluation constitutes promising diagnostic tool clinical practice; however, larger studies confirming our initial results still pending. technique. reproducibility. Instituto clinic. it. (B.M.). obtained. Overall, .000).